loading...| Preferred Name | motor neuron disease | |
| Synonyms |
ANTERIOR HORN CELL DIS motor neuron disease Neuron Diseases, Motor SECOND MOTOR NEURON DIS MOTOR NEURON DIS LOWER UPPER MOTOR NEURON DIS Anterior Horn Cell Disease LOWER MOTOR NEURON DIS MOTOR NEURON DIS UPPER Scleroses, Lateral Familial Motor Neuron Disease motor neuron disease or disorder disease of motor neuron Lateral Scleroses anterior horn cell disease FAMILIAL MOTOR NEURON DIS Sclerosis, Lateral Motor Neuron Disease, Lower MOTOR NEURON DIS SECOND Motor Neuron Disease, Upper Motor Neuron Disease, Secondary MOTOR SYSTEM DIS Motor Neuron Diseases motor neuron disorder Neuron Disease, Motor Secondary Motor Neuron Disease Upper Motor Neuron Disease Lower Motor Neuron Disease disease or disorder of motor neuron MOTOR NEURON DIS FAMILIAL Lateral Sclerosis MOTOR NEURON DIS Motor Neuron Disease, Familial Motor System Disease Motor System Diseases Scleroses, Primary Lateral disorder of motor neuron |
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| Definitions |
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) Neurological disease involving the motor neuron. |
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| ID |
http://www.ebi.ac.uk/efo/EFO_0003782 |
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| database_cross_reference |
MeSH:D016472 SNOMEDCT:37340000 MONDO:0020128 SCTID:37340000 MedDRA:10028002 MedDRA:10028003 icd11.foundation:661720689 UMLS:C0085084 MESH:D016472 MEDGEN:38785 ICD10CM:G12.2 Orphanet:98503 DOID:231 GARD:19477 ICD9:335.2 ICD9:335.8 ICD9:335.9 |
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| definition |
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) Neurological disease involving the motor neuron. |
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| disease has location | ||
| has_exact_synonym |
ANTERIOR HORN CELL DIS motor neuron disease Neuron Diseases, Motor SECOND MOTOR NEURON DIS MOTOR NEURON DIS LOWER UPPER MOTOR NEURON DIS Anterior Horn Cell Disease LOWER MOTOR NEURON DIS MOTOR NEURON DIS UPPER Scleroses, Lateral Familial Motor Neuron Disease motor neuron disease or disorder disease of motor neuron Lateral Scleroses anterior horn cell disease FAMILIAL MOTOR NEURON DIS Sclerosis, Lateral Motor Neuron Disease, Lower MOTOR NEURON DIS SECOND Motor Neuron Disease, Upper Motor Neuron Disease, Secondary MOTOR SYSTEM DIS Motor Neuron Diseases motor neuron disorder Neuron Disease, Motor Secondary Motor Neuron Disease Upper Motor Neuron Disease Lower Motor Neuron Disease disease or disorder of motor neuron MOTOR NEURON DIS FAMILIAL Lateral Sclerosis MOTOR NEURON DIS Motor Neuron Disease, Familial Motor System Disease Motor System Diseases Scleroses, Primary Lateral disorder of motor neuron |
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| id |
EFO:0003782 |
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| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_group_of_disorders http://purl.obolibrary.org/obo/mondo/mondo-base#disease_grouping |
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| label |
motor neuron disease |
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| notation |
EFO:0003782 |
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| preferred label |
motor neuron disease |
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| prefLabel |
motor neuron disease |
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| skos_closeMatch | ||
| skos_exactMatch |
http://purl.bioontology.org/ontology/ICD10CM/G12.2 http://identifiers.org/snomedct/37340000 http://purl.obolibrary.org/obo/Orphanet_98503 http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/661720689 http://purl.obolibrary.org/obo/DOID_231 http://linkedlifedata.com/resource/umls/id/C0085084 http://purl.obolibrary.org/obo/EFO_0003782 |
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| term editor |
Tomasz Adamusiak |
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| subClassOf |
http://www.ebi.ac.uk/efo/EFO_0000408 |