loading...| Preferred Name | celiac disease | |
| Synonyms |
Coeliac disease Celiac disease NOS (disorder) non tropical sprue Non-tropical sprue Non Tropical Sprue Celiac rickets Gluten-responsive sprue Gluten-Sensitive Enteropathies Nontropical Sprue Wheat-sensitive enteropathy celiac sprue Celiac disease (disorder) Idiopathic steatorrhea Coeliac disease NOS Enteropathy, Gluten Gluten Sensitive Enteropathy CD - Coeliac disease Celiac syndrome Celiac Sprue Gluten-Induced Enteropathy Enteropathies, Gluten Gluten-induced enteropathy syndrome CS - Coeliac sprue GSE - Gluten-sensitive enteropathy Sprue, Nontropical Coeliac syndrome Steatorrhoea - idiopathic coeliac sprue gluten-induced enteropathy CS - Celiac sprue Sprue, Celiac Disease, Celiac Gluten-Sensitive Enteropathy Gluten enteropathy Idiopathic steatorrhoea celiac disease Gluten Enteropathies Coeliac rickets Coeliac disease [Ambiguous] gluten intolerance Enteropathies, Gluten-Sensitive idiopathic steatorrhea Coeliac sprue Celiac disease NOS CD - Celiac disease Celiac rickets (disorder) Enteropathy, Gluten-Sensitive CELIAC DIS Sprue |
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| Definitions |
A food hypersensitivity that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite. A food allergy that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite. An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet. A malabsorption syndrome that is precipitated by the ingestion of GLUTEN-containing foods, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION. A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0001060 |
|
| database_cross_reference |
NCIt:C26714 MESH:D002446 MONDO:0005130 NCIT:C26714 ICD10CM:K90.0 MedDRA:10007864 OMIM:609753 OMIM:609755 MEDGEN:3291 SCTID:396331005 Orphanet:555 SNOMEDCT:396331005 OMIM:212750 MeSH:D002446 OMIM:612011 UMLS:C0007570 OMIMPS:212750 DOID:10608 ICD9:579.0 |
|
| definition |
A food hypersensitivity that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite. A food allergy that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite. An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet. A malabsorption syndrome that is precipitated by the ingestion of GLUTEN-containing foods, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION. A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION. |
|
| gwas_trait |
true |
|
| has_exact_synonym |
Coeliac disease Celiac disease NOS (disorder) non tropical sprue Non-tropical sprue Non Tropical Sprue Celiac rickets Gluten-responsive sprue Gluten-Sensitive Enteropathies Nontropical Sprue Wheat-sensitive enteropathy celiac sprue Celiac disease (disorder) Idiopathic steatorrhea Coeliac disease NOS Enteropathy, Gluten Gluten Sensitive Enteropathy CD - Coeliac disease Celiac syndrome Celiac Sprue Gluten-Induced Enteropathy Enteropathies, Gluten Gluten-induced enteropathy syndrome CS - Coeliac sprue GSE - Gluten-sensitive enteropathy Sprue, Nontropical Coeliac syndrome Steatorrhoea - idiopathic coeliac sprue gluten-induced enteropathy CS - Celiac sprue Sprue, Celiac Disease, Celiac Gluten-Sensitive Enteropathy Gluten enteropathy Idiopathic steatorrhoea celiac disease Gluten Enteropathies Coeliac rickets Coeliac disease [Ambiguous] gluten intolerance Enteropathies, Gluten-Sensitive idiopathic steatorrhea Coeliac sprue Celiac disease NOS CD - Celiac disease Celiac rickets (disorder) Enteropathy, Gluten-Sensitive CELIAC DIS Sprue |
|
| id |
EFO:0001060 |
|
| in_subset | ||
| label |
celiac disease |
|
| notation |
EFO:0001060 |
|
| preferred label |
celiac disease |
|
| prefLabel |
celiac disease |
|
| skos_exactMatch |
http://identifiers.org/mesh/D002446 http://identifiers.org/snomedct/396331005 http://purl.bioontology.org/ontology/ICD10CM/K90.0 http://purl.obolibrary.org/obo/DOID_10608 http://purl.obolibrary.org/obo/NCIT_C26714 http://linkedlifedata.com/resource/umls/id/C0007570 http://identifiers.org/medgen/3291 |
|
| term editor |
Tomasz Adamusiak James Malone |
|
| subClassOf |
http://www.ebi.ac.uk/efo/EFO_0000508 http://purl.obolibrary.org/obo/MONDO_0000588 |