loading...| Preferred Name | endocrine pancreas | |
| Synonyms |
islets of Langerhans part of pancreas endocrine part of pancreas endocrine pancreas pars endocrina pancreatis |
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| Definitions |
The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin. |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0000016 |
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| database_cross_reference |
MESH:D007515 EMAPA:35305 SCTID:361339003 BTO:0000650 CALOHA:TS-1302 TAO:0001260 ZFA:0001260 EFO:0002542 NCIT:C32509 VHOG:0000049 Wikipedia:Islets_of_Langerhans EV:0100129 FMA:16018 MA:0001582 |
|
| definition |
The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin. |
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| editor note |
create a separate class for distributed pancreas, eg cyclostomes? |
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| external_definition |
The zebrafish endocrine pancreas is composed of small groups of islet cells that are distributed throughout the exocrine pancreas. The islet cells produce insulin, glucagon and somatostatin.[TAO] The part of the pancreas that acts as an endocrine gland, consisting of the islets of Langerhans, which secrete insulin and other hormones. [TFD][VHOG] |
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| has_exact_synonym |
endocrine pancreas pars endocrina pancreatis |
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| has_obo_namespace |
uberon |
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| has_related_synonym |
islets of Langerhans part of pancreas endocrine part of pancreas |
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| homology_notes |
In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG] |
|
| id |
UBERON:0000016 |
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| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/uberon/core#efo_slim http://purl.obolibrary.org/obo/uberon/core#organ_slim http://purl.obolibrary.org/obo/uberon/core#vertebrate_core |
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| label |
endocrine pancreas |
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| notation |
UBERON:0000016 |
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| part_of | ||
| preferred label |
endocrine pancreas |
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| prefLabel |
endocrine pancreas |
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| RO_0002175 | ||
| taxon_notes |
endocrine and exocrine pancreas are not co-associated in hagfishes or lampreys |
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| treeView | ||
| subClassOf |