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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Imipramine | |
| Synonyms |
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|
| Definitions |
A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C62039 |
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| CAS_Registry |
50-49-7
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|
| CHEBI_ID |
CHEBI:47499
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| Chemical_Formula |
C19H24N2
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|
| code |
C62039
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| Contributing_Source |
FDA
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|
| definition |
A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. (NCI04)
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| FDA_UNII_Code |
OGG85SX4E4
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| Has_Salt_Form | ||
| in_subset | ||
| label |
Imipramine
|
|
| Legacy Concept Name |
Imipramine_Base
|
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| NCI_Drug_Dictionary_ID |
792682
|
|
| NSC Number |
169866
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| PDQ_Closed_Trial_Search_ID |
792682
|
|
| PDQ_Open_Trial_Search_ID |
792682
|
|
| Preferred_Name |
Imipramine
|
|
| prefixIRI |
NCIT:C62039
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|
| prefLabel |
Imipramine
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0020934
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| subClassOf |
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