Preferred Name | Citalopram | |
Synonyms |
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|
Definitions |
A bicyclic phthalene derivative and selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic activities. Citalopram selectively inhibits the neuronal reuptake of the neurotransmitter serotonin (5-HT) in presynaptic cells in the central nervous system, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions of serotonin on its receptors. Increased serotonergic neurotransmission results in antidepressive and anxiolytic effects. |
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ID |
http://purl.obolibrary.org/obo/NCIT_C61680 |
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CAS_Registry |
59729-33-8 |
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CHEBI_ID |
CHEBI:3723 |
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Chemical_Formula |
C20H21FN2O |
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code |
C61680 |
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Contributing_Source |
FDA |
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definition |
A bicyclic phthalene derivative and selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic activities. Citalopram selectively inhibits the neuronal reuptake of the neurotransmitter serotonin (5-HT) in presynaptic cells in the central nervous system, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions of serotonin on its receptors. Increased serotonergic neurotransmission results in antidepressive and anxiolytic effects. |
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FDA_UNII_Code |
0DHU5B8D6V |
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Has_Salt_Form | ||
in_subset | ||
label |
Citalopram |
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Legacy Concept Name |
Citalopram |
|
Preferred_Name |
Citalopram |
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prefixIRI |
NCIT:C61680 |
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prefLabel |
Citalopram |
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Semantic_Type |
Pharmacologic Substance |
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UMLS_CUI |
C0008845 |
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subClassOf |