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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Folic Acid | |
| Synonyms |
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| Definitions |
A collective term for pteroylglutamic acids and their oligoglutamic acid conjugates. As a natural water-soluble substance, folic acid is involved in carbon transfer reactions of amino acid metabolism, in addition to purine and pyrimidine synthesis, and is essential for hematopoiesis and red blood cell production. (NCI05) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C510 |
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| ALT_DEFINITION |
Synthetic folate in fortified foods and supplements containing a single glutamate molecule. A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Folate helps to make red blood cells. It is found in whole-grain breads and cereals, liver, green vegetables, orange juice, lentils, beans, and yeast. Folate is water-soluble (can dissolve in water) and must be taken in every day. Not enough folate can cause anemia (a condition in which the number of red blood cells is below normal), diseases of the heart and blood vessels, and defects in the brain and spinal cord in a fetus. Folate is being studied with vitamin B12 in the prevention and treatment of cancer.
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| CAS_Registry |
59-30-3
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| CHEBI_ID |
CHEBI:27470
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| Chemical_Formula |
C19H19N7O6
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| code |
C510
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| Contributing_Source |
CRCH CTRP FDA
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|
| definition |
A collective term for pteroylglutamic acids and their oligoglutamic acid conjugates. As a natural water-soluble substance, folic acid is involved in carbon transfer reactions of amino acid metabolism, in addition to purine and pyrimidine synthesis, and is essential for hematopoiesis and red blood cell production. (NCI05)
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| Display_Name |
Folic Acid
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| FDA_UNII_Code |
935E97BOY8
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C157711 |
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| INFOODS |
FOLAC
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| Is_Value_For_GDC_Property | ||
| label |
Folic Acid
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| Legacy Concept Name |
Folic_Acid
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| Maps_To |
Folic Acid
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| NCI_Drug_Dictionary_ID |
39641
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| NSC Number |
3073
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| PDQ_Closed_Trial_Search_ID |
39641
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| PDQ_Open_Trial_Search_ID |
39641
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| Preferred_Name |
Folic Acid
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| prefixIRI |
NCIT:C510
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| prefLabel |
Folic Acid
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| Semantic_Type |
Organic Chemical Vitamin
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| Tolerable_Level |
Y
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| UMLS_CUI |
C0016410
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| Unit |
mcg
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| US_Recommended_Intake |
Y* (*for women of childbearing age)
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| USDA_ID |
431
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| subClassOf |
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