Preferred Name |
Medulloblastoma |
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Synonyms |
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Definitions |
A malignant, invasive embryonal neoplasm arising from the cerebellum or posterior fossa. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: classic medulloblastoma, large cell/anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, and medulloblastoma with extensive nodularity. |
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ID |
http://purl.obolibrary.org/obo/NCIT_C3222 |
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ALT_DEFINITION |
A malignant, invasive embryonal neoplasm arising from the cerebellum. A malignant brain tumor that begins in the lower part of the brain and that can spread to the spine or to other parts of the body. Medulloblastomas are a type of primitive neuroectodermal tumor (PNET). A rapidly progressive cancer of the brain that originates in the cerebellum. |
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code |
C3222 |
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Contributing_Source |
Cellosaurus CDISC CTEP GDC MedDRA NICHD |
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definition |
A malignant, invasive embryonal neoplasm arising from the cerebellum or posterior fossa. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: classic medulloblastoma, large cell/anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, and medulloblastoma with extensive nodularity. |
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ICD-O-3_Code |
9470/3 |
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in_subset |
http://purl.obolibrary.org/obo/NCIT_C77526 http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C102905 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/ncit#oncotree_slim http://purl.obolibrary.org/obo/NCIT_C118464 http://purl.obolibrary.org/obo/NCIT_C126659 http://purl.obolibrary.org/obo/NCIT_C103046 http://purl.obolibrary.org/obo/NCIT_C88025 http://purl.obolibrary.org/obo/NCIT_C165258 http://purl.obolibrary.org/obo/NCIT_C157711 |
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Is_Value_For_GDC_Property | ||
label |
Medulloblastoma |
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Legacy Concept Name |
Medulloblastoma |
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Maps_To |
CNS, medulloblastoma Medulloblastoma |
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Neoplastic_Status |
Malignant |
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Preferred_Name |
Medulloblastoma |
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prefixIRI |
NCIT:C3222 |
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prefLabel |
Medulloblastoma |
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Semantic_Type |
Neoplastic Process |
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UMLS_CUI |
C0025149 |
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subClassOf |
http://purl.obolibrary.org/obo/NCIT_C3569 |