loading...| Preferred Name |
Acute Myeloid Leukemia |
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| Synonyms |
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| Definitions |
A clonal expansion of myeloid blasts in the bone marrow, blood or other tissues. The classification of acute myeloid leukemias (AMLs) encompasses four major categories: 1) AML with recurrent genetic abnormalities; 2) AML with multilineage dysplasia; 3) Therapy-related AML; 4) AML not otherwise specified. The required bone marrow or peripheral blood blast percentage for the diagnosis of AML is 20% (WHO classification). |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C3171 |
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| ALT_DEFINITION |
A rapidly progressive cancer of the blood and bone marrow consisting of the proliferation of abnormal myeloblasts, which are immature, dysfunctional white blood cells. An aggressive (fast-growing) disease in which too many myeloblasts (immature white blood cells that are not lymphoblasts) are found in the bone marrow and blood. |
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| code |
C3171 |
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| Contributing_Source |
Cellosaurus CPTAC CTRP GDC MedDRA NICHD |
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| definition |
A clonal expansion of myeloid blasts in the bone marrow, blood or other tissues. The classification of acute myeloid leukemias (AMLs) encompasses four major categories: 1) AML with recurrent genetic abnormalities; 2) AML with multilineage dysplasia; 3) Therapy-related AML; 4) AML not otherwise specified. The required bone marrow or peripheral blood blast percentage for the diagnosis of AML is 20% (WHO classification). |
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| Display_Name |
Acute Myeloid Leukemia (AML) |
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| ICD-O-3_Code |
9861/3 |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C138190 http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C159328 http://purl.obolibrary.org/obo/ncit#oncotree_slim http://purl.obolibrary.org/obo/NCIT_C175325 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C118464 http://purl.obolibrary.org/obo/NCIT_C159338 http://purl.obolibrary.org/obo/NCIT_C132009 http://purl.obolibrary.org/obo/NCIT_C126659 http://purl.obolibrary.org/obo/NCIT_C138188 http://purl.obolibrary.org/obo/NCIT_C165258 http://purl.obolibrary.org/obo/NCIT_C118168 |
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| Is_Value_For_GDC_Property |
http://purl.obolibrary.org/obo/NCIT_C177615 |
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| label |
Acute Myeloid Leukemia |
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| Legacy Concept Name |
Acute_Myeloid_Leukemia |
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| Maps_To |
Acute myeloblastic leukemia, not having achieved remission Acute myelocytic leukemia Acute myeloid leukemia without mention of having achieved remission Acute myeloblastic leukemia Acute granulocytic leukemia Acute myelogenous leukemia Acute non-lymphocytic leukemia Myeloid leukemia, acute Acute myeloid leukemia Acute myeloid leukemia (AML) Acute myeloblastic leukaemia [AML] 9861/3 9872/3 |
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| Neoplastic_Status |
Malignant |
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| Preferred_Name |
Acute Myeloid Leukemia |
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| prefixIRI |
NCIT:C3171 |
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| prefLabel |
Acute Myeloid Leukemia |
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| Semantic_Type |
Neoplastic Process |
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| UMLS_CUI |
C4015937 |
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| subClassOf |