loading...| Preferred Name | Inflammation | |
| Synonyms |
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| Definitions |
A finding of a localized protective response resulting from injury or destruction of tissues. Inflammation serves to destroy, dilute, or wall off both the injurious agent and the injured tissue. In the acute phase, inflammation is characterized by the signs of pain, heat, redness, swelling, and loss of function. Histologically, inflammation involves a complex series of events, including dilatation of arterioles, capillaries, and venules, with increased permeability and blood flow; exudation of fluids, including plasma proteins; and leukocyte migration into the site of inflammation. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C3137 |
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| ALT_DEFINITION |
A response to an injury or abnormal stimuli characterized by inflammatory cell infiltration and varying degrees of vascular and tissue reactions (hyperemia, edema, fibrin, and/or fibrosis). A localized physical condition in which part of the body becomes reddened, swollen, or hot and often painful. Redness, swelling, pain, and/or a feeling of heat in an area of the body. This is a protective reaction to injury, disease, or irritation of the tissues. |
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| code |
C3137 |
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| Contributing_Source |
CDISC FDA GDC |
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| database_cross_reference |
IMDRF:E2326 |
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| definition |
A finding of a localized protective response resulting from injury or destruction of tissues. Inflammation serves to destroy, dilute, or wall off both the injurious agent and the injured tissue. In the acute phase, inflammation is characterized by the signs of pain, heat, redness, swelling, and loss of function. Histologically, inflammation involves a complex series of events, including dilatation of arterioles, capillaries, and venules, with increased permeability and blood flow; exudation of fluids, including plasma proteins; and leukocyte migration into the site of inflammation. |
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| FDA_Table |
Patient Code (Appendix B) |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C62596 http://purl.obolibrary.org/obo/NCIT_C77526 http://purl.obolibrary.org/obo/NCIT_C120531 http://purl.obolibrary.org/obo/NCIT_C54450 http://purl.obolibrary.org/obo/NCIT_C177537 |
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| Is_Value_For_GDC_Property | ||
| label |
Inflammation |
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| Legacy Concept Name |
Inflammation |
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| Maps_To |
Inflammation Inflammation, Hyperkeratosis |
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| Preferred_Name |
Inflammation |
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| prefixIRI |
NCIT:C3137 |
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| prefLabel |
Inflammation |
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| Semantic_Type |
Finding |
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| UMLS_CUI |
C0021368 |
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| subClassOf |