loading...| Preferred Name | Choriocarcinoma | |
| Synonyms |
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| Definitions |
An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C2948 |
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| ALT_DEFINITION |
A malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta). Almost all choriocarcinomas form in the uterus after fertilization of an egg by a sperm, but a small number form in a testis or an ovary. Choriocarcinomas spread through the blood to other organs, especially the lungs. They are a type of gestational trophoblastic disease. A malignant neoplasm arising from placental trophoblast cells. They generally arise in the uterus. |
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| code |
C2948 |
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| Contributing_Source |
CDISC CPTAC CTRP GDC PCDC |
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| definition |
An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected. |
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| Display_Name |
Choriocarcinoma |
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| ICD-O-3_Code |
9100/3 |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C138190 http://purl.obolibrary.org/obo/NCIT_C168658 http://purl.obolibrary.org/obo/NCIT_C168656 http://purl.obolibrary.org/obo/NCIT_C168657 http://purl.obolibrary.org/obo/NCIT_C168655 http://purl.obolibrary.org/obo/NCIT_C77526 http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C168662 http://purl.obolibrary.org/obo/NCIT_C168661 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/ncit#oncotree_slim http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C126659 http://purl.obolibrary.org/obo/NCIT_C177396 http://purl.obolibrary.org/obo/NCIT_C138188 http://purl.obolibrary.org/obo/NCIT_C88025 http://purl.obolibrary.org/obo/NCIT_C118168 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C156966 |
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| Is_PCDC_GCT_Permissible_Value_For_Variable | ||
| Is_Value_For_GDC_Property | ||
| label |
Choriocarcinoma |
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| Legacy Concept Name |
Choriocarcinoma |
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| Maps_To |
Choriocarcinoma, NOS Chorionepithelioma Chorioepithelioma 9100/3 |
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| Neoplasm_Has_Special_Category | ||
| Neoplastic_Status |
Malignant |
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| Preferred_Name |
Choriocarcinoma |
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| prefixIRI |
NCIT:C2948 |
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| prefLabel |
Choriocarcinoma |
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| Semantic_Type |
Neoplastic Process |
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| UMLS_CUI |
C0008497 |
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| subClassOf |