Preferred Name

Aminoglycoside Antibiotic
Synonyms
Definitions

Any antibiotic containing amino-modified sugars originally isolated from various Streptomyces and Micromonospora species. Aminoglycoside antibiotics bind to the 16S RNA of the bacterial 30S ribosomal subunit, inhibiting translation and protein synthesis. Aminoglycoside use is associated with ototoxicity, neurotxicity and nephrotoxicity.

ID

http://purl.obolibrary.org/obo/NCIT_C2363

ALT_DEFINITION

A family of antibiotics that works against many types of bacteria and includes streptomycin, gentamicin, and neomycin. Aminoglycosides are used to treat bacterial infections.

CHEBI_ID

CHEBI:22507

code

C2363

definition

Any antibiotic containing amino-modified sugars originally isolated from various Streptomyces and Micromonospora species. Aminoglycoside antibiotics bind to the 16S RNA of the bacterial 30S ribosomal subunit, inhibiting translation and protein synthesis. Aminoglycoside use is associated with ototoxicity, neurotxicity and nephrotoxicity.

label

Aminoglycoside Antibiotic

Legacy Concept Name

Aminoglycoside_Antibiotic

Preferred_Name

Aminoglycoside Antibiotic

prefixIRI

NCIT:C2363

prefLabel

Aminoglycoside Antibiotic

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C3536841

subClassOf

http://purl.obolibrary.org/obo/NCIT_C784

http://purl.obolibrary.org/obo/NCIT_C258

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