loading...| Preferred Name | Glucocorticoid | |
| Synonyms |
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| Definitions |
A corticosteroid that supports a variety of cardiovascular, metabolic, immunologic, and homeostatic functions, and which binds specifically to the glucocorticoid receptor (GR; NR3C1). Glucocorticoid binding to GR leads to the transportation of the activated receptor-glucocorticoid complex to the nucleus, after which it binds to glucocorticoid response elements (GRE) and regulates the expression of GR-responsive genes. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C2323 |
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| ALT_DEFINITION |
A group of corticosteroids that affect carbohydrate metabolism, inhibit corticotropin secretion, and possess pronounced anti-inflammatory activity. A compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs). |
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| CHEBI_ID |
CHEBI:24261 |
|
| code |
C2323 |
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| Contributing_Source |
CTRP NICHD |
|
| definition |
A corticosteroid that supports a variety of cardiovascular, metabolic, immunologic, and homeostatic functions, and which binds specifically to the glucocorticoid receptor (GR; NR3C1). Glucocorticoid binding to GR leads to the transportation of the activated receptor-glucocorticoid complex to the nucleus, after which it binds to glucocorticoid response elements (GRE) and regulates the expression of GR-responsive genes. |
|
| Display_Name |
Glucocorticoid |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C116977 |
|
| label |
Glucocorticoid |
|
| Legacy Concept Name |
Glucocorticoid |
|
| Preferred_Name |
Glucocorticoid |
|
| prefixIRI |
NCIT:C2323 |
|
| prefLabel |
Glucocorticoid |
|
| Semantic_Type |
Organic Chemical Hormone |
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| UMLS_CUI |
C0017710 |
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| subClassOf |