Preferred Name

Polyketide

Synonyms
Definitions

A structurally diverse group of compounds created by repeated condensations and modifications catalyzed by polyketide synthases (PKSs). Polyketides may be derived from malonyl- and methylmalonyl-coenzyme A (CoA) extender units and simple acyl-CoA starter units, such as acetyl-, propionyl-, and isobutyryl-CoA. It includes numerous antimicrobial, antiparasitic, and anticancer agents such as erythromycins, tetracylines, nystatins, avermectins and antitumor epothilones, as well as some potent toxins.

ID

http://purl.obolibrary.org/obo/NCIT_C180968

code

C180968

definition

A structurally diverse group of compounds created by repeated condensations and modifications catalyzed by polyketide synthases (PKSs). Polyketides may be derived from malonyl- and methylmalonyl-coenzyme A (CoA) extender units and simple acyl-CoA starter units, such as acetyl-, propionyl-, and isobutyryl-CoA. It includes numerous antimicrobial, antiparasitic, and anticancer agents such as erythromycins, tetracylines, nystatins, avermectins and antitumor epothilones, as well as some potent toxins.

label

Polyketide

NCI_META_CUI

CL1663543

Preferred_Name

Polyketide

prefixIRI

NCIT:C180968

prefLabel

Polyketide

Semantic_Type

Organic Chemical

subClassOf

http://purl.obolibrary.org/obo/NCIT_C616

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