loading...| Preferred Name |
Escitalopram |
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| Synonyms |
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| ID |
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClassc69266a3_da9a_4e45_86c7_af75a6ac9ff4 |
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| Chinese |
艾斯西酞普兰 |
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| label |
Escitalopram |
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| MESH_Definition |
S-enantiomer of citalopram. |
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| NCIt_Definition |
The active S-stereoisomer of the selective serotonin reuptake inhibitor (SSRI) citalopram with antidepressant, anti-obsessive-compulsive and antibulimic properties. Escitalopram inhibits the reuptake of the neurotransmitter serotonin (5-HT) at the serotonin reuptake pump of the neuronal membrane of the presynaptic cell, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions of serotonin on 5HT1A autoreceptors. Unlike other SSRIs, escitalopram appears to not only bind to a primary high-affinity site on the serotonin transporter protein but also to a secondary lower-affinity allosteric site that is considered to stabilize and prolong drug binding. |
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| prefLabel |
Escitalopram |
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| Synonyms |
ESCITALOPRAM Product containing escitalopram (medicinal product) escitalopram Escitalopram (substance) (+)-Citalopram S-(+)-Citalopram Seroplex Escitalopram Escitalopramum S(+)-Citalopram (S)-Citalopram Escitalopram-containing product Escitalopram Oxalate Cytalopram Lu-10-171 Lu10171 Celexa Seropram Citalopram Hydrobromide Lexapro |
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