loading...| Preferred Name |
Gabapentin |
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| Synonyms |
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| ID |
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClassb006522d_2803_4ec9_a993_eedf522f7361 |
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| Chinese |
加巴喷丁 |
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| label |
Gabapentin |
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| MESH_Definition |
A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME. |
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| NCIt_Definition |
A synthetic analogue of the neurotransmitter gamma-aminobutyric acid with anticonvulsant activity. Although its exact mechanism of action is unknown, gabapentin appears to inhibit excitatory neuron activity. This agent also exhibits analgesic properties. (NCI04) |
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| prefLabel |
Gabapentin |
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| ROCG_Guidance |
[GRADES OF RECOMMENDATION:C] All methods of contraception may be offered to women taking non-enzyme-inducing AEDs (e.g. sodium valproate, levetiracetam, gabapentin, vigabatrin, tiagabine and pregabalin). 【推荐等级：C】所有避孕方法都适用于服用非酶诱导AEDs的WWE（丙戊酸钠、左乙拉西坦、加巴喷丁、氨己烯酸、替加宾、普瑞巴林）。 https://www.rcog.org.uk/guidance/browse-all-guidance/green-top-guidelines/epilepsy-in-pregnancy-green-top-guideline-no-68/ |
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| SIGN_Guidance |
[GRADES OF RECOMMENDATION:D] Parents should be made aware of signs of toxicity in infants of breastfeeding women taking antiepileptic drugs. The possibility of sedation should be considered in infants of mothers taking high dose antiepileptic drugs, polytherapy, or regimens including primidone, levetiracetam, gabapentin, lamotrigine and topiramate. D级推荐：应告知女性癫痫患者及其伴侣，哺乳期服用AEDs可能对新生儿/婴儿有不良影响。服用大剂量AEDs、综合疗法或采用包含扑米酮、左乙拉西坦、加巴喷丁、拉莫三嗪和托吡酯在内的治疗方案的哺乳期母亲婴儿可能会有镇静的副作用。 Scottish Intercollegiate Guidelines Network.Diagnosis and management of epilepsy in adults. SIGN 143. Edinburgh, SIGN, 2015. Available at: www.sign.ac.uk/guidelines/fulltext/143/index.html |
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| Synonyms |
Convalis Gabapentino 60142-96-3 Neurontin gabapentin Product containing gabapentin (medicinal product) 1-(aminomethyl)cyclohexaneacetic Acid Gabapentinum Gabapentina Gabapentin-containing product Gabapentin (substance) Gralise Gabapentine Apo-Gabapentin ApoGabapentin Gabapentin Hexal Apo Gabapentin Novo Gabapentin Novo-Gabapentin Gabapentin Ratiopharm NovoGabapentin Gabapentin-Ratiopharm Gabapentin Stada PMS-Gabapentin |
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| subClassOf |