Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

white pulp of spleen

Synonyms

spleen white pulp

splenic white pulp

pulpa alba

white pulp

noduli lymphoidei splenici

Definitions

The parenchymatous tissue of the spleen that surrounds splenic blood vessels, consists of compact masses of lymphatic cells and is where foreign material removed from the blood is used to initiate an immune reaction that results in the production of antibodies.

ID

http://purl.obolibrary.org/obo/UBERON_0001959

composed primarily of

http://purl.obolibrary.org/obo/CL_0000542

contributes to morphology of

http://purl.obolibrary.org/obo/UBERON_0002106

database_cross_reference

EMAPA:35809

Wikipedia:White_pulp

UMLS:C0229686

NCIT:C12993

CALOHA:TS-1264

FMA:62805

MA:0000762

definition

The parenchymatous tissue of the spleen that surrounds splenic blood vessels, consists of compact masses of lymphatic cells and is where foreign material removed from the blood is used to initiate an immune reaction that results in the production of antibodies.

depiction

http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1191.png

has exact synonym

spleen white pulp

splenic white pulp

pulpa alba

white pulp

has related synonym

noduli lymphoidei splenici

has_obo_namespace

uberon

id

UBERON:0001959

in_subset

http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

white pulp of spleen

notation

UBERON:0001959

prefixIRI

UBERON:0001959

prefLabel

white pulp of spleen

RO_0002175

http://purl.obolibrary.org/obo/NCBITaxon_9606

UBPROP_0000009

The white pulp contains T cells, B cells and accessory cells. The function of the white pulp is to mount an immunological response to antigens within the blood. The white pulp is present in the form of a periarteriolar lymphoid sheath. This sheath contains B cell follicles and T cells. At the edge of the T zone is a region known as the marginal zone where larger lymphocytes and antigen presenting dendritic cells are located. [Wikipedia:White_pulp]

subClassOf

http://purl.obolibrary.org/obo/UBERON_1000023

http://purl.obolibrary.org/obo/PR_000050567

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