Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

obsolete necrotic cell death

Synonyms

necrosis

cellular necrosis

Definitions

The reason for obsoletion is that this term represent an assay and not a GO process. The reason for obsoletion is that this represents a phenotype. OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues.

ID

http://purl.obolibrary.org/obo/GO_0070265

Obsolete

true

comment

The reason for obsoletion is that this term represent an assay and not a GO process. The reason for obsoletion is that this represents a phenotype.

definition

OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues.

deprecated

true

has broad synonym

necrosis

has exact synonym

cellular necrosis

has_obo_namespace

biological_process

id

GO:0070265

label

obsolete necrotic cell death

notation

GO:0070265

prefixIRI

GO:0070265

prefLabel

obsolete necrotic cell death

term tracker item

https://github.com/geneontology/go-ontology/issues/24680

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