Preferred Name |
Sulbactam |
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Synonyms |
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ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Sulbactam |
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definition |
A semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity. |
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label |
Sulbactam |
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prefixIRI |
Sulbactam |
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prefLabel |
Sulbactam |
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reference | ||
Synonyms |
(2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid 4,4-dioxide CP 45899 SULBACTAM Sulbactam |
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subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Beta-Lactam_Antibiotic |