loading...| Preferred Name |
Bone Pain |
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| Synonyms |
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| Definitions |
An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to bone. |
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| ID |
http://purl.obolibrary.org/obo/HP_0002653 |
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| curator note |
Provide source for additional info. |
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| database cross reference |
HP:0002653 |
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| definition |
An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to bone. |
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| definition source | ||
| existence in other ontologies |
Sufficient |
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| in guideline |
http://purl.obolibrary.org/obo/SCDO_1000150 http://purl.obolibrary.org/obo/SCDO_1000151 http://purl.obolibrary.org/obo/SCDO_1000154 http://purl.obolibrary.org/obo/SCDO_1000152 http://purl.obolibrary.org/obo/SCDO_1000144 http://purl.obolibrary.org/obo/SCDO_1000149 http://purl.obolibrary.org/obo/SCDO_1000148 http://purl.obolibrary.org/obo/SCDO_1000146 |
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| is caused by |
A number of diseases may cause bone pain including osteoarthritis, Paget's disease, sickle cell anemia, and bone cancer. Acute leukemia;Acute rheumatic fever, a very dangerous disease that can cause permanent cardiac damage. Bursitis;Fibromyalgia like disease has been studied as a cause of joint pain in the child.Hypermobility syndrome can present with knee or ankle pain;Injury such as a fracture. Juvenile rheumatoid arthritis;Lupus;Lyme disease, which is transmitted by ticks and is characterized by debilatating polyarthritis, neurologic symptoms, and erythema migrans.;Osteomyelitis;Osteosarcoma.Septic arthritis, a severe infection of the joint that can lead to permanent joint damage.Synovitis;Viral diseases, including the measles, influenza, mononucleosis, chickenpox, and mumps. |
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| is characterised by |
Stimulation of specialized pain-sensitive nerve fibers (nociceptors) that innervate bone tissue leads to the sensation of bone pain. Bone pain originates from both the periosteum and the bone marrow which relay nociceptive signals to the brain creating the sensation of pain. Bone tissue is innervated by both myelinated (A beta and A delta fiber) and unmyelinated (C fiber) sensory neurons. In combination, they can provide an initial burst of pain, initiated by the faster myelinated fibers, followed by a slower and longer lasting dull pain initiated by unmyelinated fibers |
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| prefixIRI |
HP:0002653 |
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| prefLabel |
Bone Pain |
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| previous identifier |
SCDO:0000154 |
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| rdfs:label |
Bone Pain |
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| treated with |
http://purl.obolibrary.org/obo/SCDO_1000017 |
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| subClassOf |