G protein coupled receptors

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G protein coupled receptors

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http://journals.plos.org/plosone/browse/g_protein_coupled_receptors

G protein coupled receptors

10.60.280.840.20^G protein coupled receptors|10.120.230.150.20^G protein coupled receptors

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G-protein coupled receptors (GPCRs) are the largest group of plasma membrane receptors of which rhodopsin and adrenergic receptors are the most familiar. They are integral plasma membrane proteins that transduce signals from extracellular ligands to signals in intracellular relay proteins, the heterotrimeric GTP binding proteins (G proteins). By coupling to many downstream effectors, the G proteins initiate pleiotropic changes in many targets. Thus, the extracellular signal is typically amplified to produce robust, varied, and cell-specific responses. http://www.scholarpedia.org/article/G_protein-coupled_receptor RD

Accepted

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