Preferred Name |
cefixime |
|
Synonyms |
7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido}-3-ethenyl-3,4-didehydrocepham-4-carboxylic acid (-)-cefixim (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefixima cefixime cefiximum |
|
Definitions |
A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_472657 |
|
charge |
0 |
|
database_cross_reference |
Patent:US4409214 KEGG:C06881 Patent:EP30630 DrugBank:DB00671 CAS:79350-37-1 PMID:29017833 Drug_Central:537 PMID:17116681 KEGG:D00258 Beilstein:6025058 |
|
formula |
C16H15N5O7S2 |
|
has role | ||
has_alternative_id |
CHEBI:3487 |
|
has_exact_synonym |
7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido}-3-ethenyl-3,4-didehydrocepham-4-carboxylic acid |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
(-)-cefixim (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefixima cefixime cefiximum |
|
id |
CHEBI:472657 |
|
in_subset | ||
inchi |
InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9-/t10-,14-/m1/s1 |
|
inchikey |
OKBVVJOGVLARMR-QSWIMTSFSA-N |
|
label |
cefixime |
|
mass |
453.45000 |
|
monoisotopicmass |
453.04129 |
|
notation |
CHEBI:472657 |
|
prefLabel |
cefixime |
|
smiles |
[H][C@]12SCC(C=C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC(O)=O)\c1csc(N)n1)C(O)=O |
|
textual definition |
A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections. |
|
subClassOf |