loading...| Preferred Name |
obsolete necrotic cell death |
|
| Synonyms |
necrosis cellular necrosis |
|
| Definitions |
The reason for obsoletion is that this term represent an assay and not a GO process. The reason for obsoletion is that this represents a phenotype. OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues. |
|
| ID |
http://purl.obolibrary.org/obo/GO_0070265 |
|
| Obsolete |
true |
|
| comment |
The reason for obsoletion is that this term represent an assay and not a GO process. The reason for obsoletion is that this represents a phenotype. |
|
| deprecated |
true |
|
| has_broad_synonym |
necrosis |
|
| has_exact_synonym |
cellular necrosis |
|
| has_obo_namespace |
biological_process |
|
| IAO_0000233 | ||
| id |
GO:0070265 |
|
| label |
obsolete necrotic cell death |
|
| notation |
GO:0070265 |
|
| prefLabel |
obsolete necrotic cell death |
|
| textual definition |
OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues. |