Preferred Name |
anidulafungin |
|
Synonyms |
VER-002 |
|
Definitions |
A cyclic lipopeptide echinocandin derivative with antifungal activity. Anidulafungin inhibits 1,3 beta-D-glucan synthase, an enzyme involved in fungal cell wall synthesis, resulting in cell lysis and death. This agent is active against Candida species and Aspergillus. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C38716" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38716" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000328242 |
|
altLabel |
VER-002 LY303366 V-echinocandin Eraxis |
|
cui |
C1142738 C1527264 C1697348 C0532508 |
|
DATE FIRST PUBLISHED |
2003-08-24 |
|
Date last modified |
2008-05-23 |
|
definition |
A cyclic lipopeptide echinocandin derivative with antifungal activity. Anidulafungin inhibits 1,3 beta-D-glucan synthase, an enzyme involved in fungal cell wall synthesis, resulting in cell lysis and death. This agent is active against Candida species and Aspergillus. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C38716" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38716" NCI Thesaurus) |
|
LT |
TRD |
|
NCI ID |
C38716 |
|
notation |
CDR0000328242 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
anidulafungin |
|
tui |
T116 T121 |