loading...| Preferred Name |
ursodiol |
|
| Synonyms |
Deursil |
|
| Definitions |
A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1818" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1818" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000306453 |
|
| altLabel |
Deursil UDCA ursodeoxycholic acid Actigall (3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid URSO |
|
| CAS Registry |
128-13-2 |
|
| cui |
C0042105 C0718244 C1519841 C0724157 |
|
| DATE FIRST PUBLISHED |
2003-05-23 |
|
| Date last modified |
2006-09-28 |
|
| definition |
A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1818" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1818" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C1818 |
|
| notation |
CDR0000306453 |
|
| NSC Code |
683769 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
ursodiol |
|
| tui |
T109 T123 T121 |