Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

therapeutic epinephrine

Synonyms

epi

Definitions

The synthetic form of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities. By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C473" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C473" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000041857

altLabel

epi

adrenaline

epinephrine

cui

C0014563

Date last modified

2008-10-16

definition

The synthetic form of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities. By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C473" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C473" NCI Thesaurus)

Legacy PDQ ID

5069

NCI ID

C473

notation

CDR0000041857

ORIG STY

Drug/agent

prefLabel

therapeutic epinephrine

tui

T125

T109

T121

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http://purl.bioontology.org/ontology/UATC/A01AD01 ATC CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387362001 SNOMEDCT CUI
http://purl.bioontology.org/ontology/RCD/X80FK RCD CUI
http://purl.bioontology.org/ontology/SCTSPA/387362001 SCTSPA CUI
http://purl.bioontology.org/ontology/UATC/B02BC09 ATC CUI
http://purl.bioontology.org/ontology/UATC/R01AA14 ATC CUI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C473 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C473 NCIT LOOM
http://purl.bioontology.org/ontology/UATC/R03AA01 ATC CUI
http://purl.bioontology.org/ontology/CSP/2268-5502 CRISP CUI
http://purl.bioontology.org/ontology/RXNORM/3992 RXNORM CUI
http://purl.bioontology.org/ontology/MESH/D004837 MESH CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146377 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006261 NDFRT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/65502005 SNOMEDCT CUI
http://purl.bioontology.org/ontology/MSHFRE/D004837 MSHFRE CUI
http://purl.bioontology.org/ontology/UATC/S01EA01 ATC CUI
http://purl.bioontology.org/ontology/NDDF/001774 NDDF CUI
http://purl.bioontology.org/ontology/SNMI/C-68060 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/F-B2110 SNMI CUI
http://purl.bioontology.org/ontology/LNC/LP15027-3 LOINC CUI
http://purl.bioontology.org/ontology/RCD/x02LH RCD CUI
http://purl.bioontology.org/ontology/UATC/C01CA24 ATC CUI
http://purl.bioontology.org/ontology/LNC/MTHU002341 LOINC CUI
http://purl.bioontology.org/ontology/VANDF/4018034 VANDF CUI
http://purl.bioontology.org/ontology/SCTSPA/65502005 SCTSPA CUI