loading...| Preferred Name |
epoetin alfa |
|
| Synonyms |
r-HuEPO |
|
| Definitions |
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine human erythropoietin (EPO). Produced primarily by cells of the peritubular capillary endothelium of the kidney in response to hypoxia, circulating EPO binds to EPO receptors on the surface of committed erythroid progenitors in the bone marrow resulting in their replication and maturation into functional erythrocytes. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2695" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2695" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000041102 |
|
| altLabel |
r-HuEPO Procrit Retacrit Epogen EPO erythropoietin Eprex |
|
| CAS Registry |
113427-24-0 |
|
| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000042081 http://purl.bioontology.org/ontology/PDQ/CDR0000042184 http://purl.bioontology.org/ontology/PDQ/CDR0000041764 http://purl.bioontology.org/ontology/PDQ/CDR0000405822 http://purl.bioontology.org/ontology/PDQ/CDR0000038524 http://purl.bioontology.org/ontology/PDQ/CDR0000038331 http://purl.bioontology.org/ontology/PDQ/CDR0000042696 http://purl.bioontology.org/ontology/PDQ/CDR0000042080 http://purl.bioontology.org/ontology/PDQ/CDR0000042165 http://purl.bioontology.org/ontology/PDQ/CDR0000304395 http://purl.bioontology.org/ontology/PDQ/CDR0000269052 http://purl.bioontology.org/ontology/PDQ/CDR0000041451 http://purl.bioontology.org/ontology/PDQ/CDR0000043153 |
|
| cui |
C0700704 C3642486 C0357126 C0376541 C0376539 C0733467 C0014822 |
|
| Date last modified |
2018-05-15 |
|
| definition |
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine human erythropoietin (EPO). Produced primarily by cells of the peritubular capillary endothelium of the kidney in response to hypoxia, circulating EPO binds to EPO receptors on the surface of committed erythroid progenitors in the bone marrow resulting in their replication and maturation into functional erythrocytes. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2695" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2695" NCI Thesaurus) |
|
| Legacy PDQ ID |
4143 |
|
| LT |
TRD |
|
| NCI ID |
C2695 |
|
| notation |
CDR0000041102 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
epoetin alfa |
|
| tui |
T125 T116 T129 T121 |