Physician Data Query

Last uploaded: July 6, 2018
Preferred Name

medroxyprogesterone

Synonyms

Provera Dosepak

Definitions

A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39813&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39813&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C629" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039813

altLabel

Provera Dosepak

Provera

(6Alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione

6Alpha-methyl-17alpha-hydroxyprogesterone

6Alpha-methyl-4-pregnen-17alpha-ol-3,20-dione

17Alpha-hydroxy-6alpha-methylprogesterone

MPA

Depo-Provera

medroxyprogesterone acetate

Curretab

CAS Registry

520-85-4

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000040343

http://purl.bioontology.org/ontology/PDQ/CDR0000039121

http://purl.bioontology.org/ontology/PDQ/CDR0000038466

http://purl.bioontology.org/ontology/PDQ/CDR0000041475

http://purl.bioontology.org/ontology/PDQ/CDR0000040448

cui

C0699704

C0338069

C0699700

C0065864

C0025147

C0699702

Date last modified

2006-08-29

definition

A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39813&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39813&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C629" NCI Thesaurus)

Legacy PDQ ID

249

LT

TRD

NCI ID

C629

notation

CDR0000039813

NSC Code

27408

ORIG STY

Drug/agent

prefLabel

medroxyprogesterone

tui

T125

T109

T121

T203

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http://purl.bioontology.org/ontology/RCD/x04u4 RCD CUI
http://purl.jp/bio/4/id/200906004151067745 IOBC LOOM
http://purl.jp/bio/4/id/200906004151067745 IOBC LOOM
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http://purl.bioontology.org/ontology/NDDF/004938 NDDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147899 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147899 NDFRT LOOM
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http://www.drugbank.ca/drugs/DB00603 FTC LOOM
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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.745.745.654.829.614 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/G03DA02 ATC CUI
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C629 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C629 NCIT LOOM
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http://purl.bioontology.org/ontology/RXNORM/1000112 RXNORM CUI
http://purl.bioontology.org/ontology/SCTSPA/126113007 SCTSPA CUI
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http://purl.bioontology.org/ontology/SCTSPA/27707001 SCTSPA CUI
http://purl.bioontology.org/ontology/UATC/L02AB02 ATC CUI
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http://purl.bioontology.org/ontology/MESH/D017258 MESH CUI
http://purl.bioontology.org/ontology/MESH/D017258 MESH CUI
http://purl.bioontology.org/ontology/MESH/D017258 MESH CUI
http://purl.bioontology.org/ontology/MESH/D017258 MESH CUI
http://purl.bioontology.org/ontology/CSP/2422-8564 CRISP CUI
http://purl.bioontology.org/ontology/CSP/2422-8564 CRISP CUI
http://purl.bioontology.org/ontology/CSP/2422-8564 CRISP LOOM
http://purl.obolibrary.org/obo/CHEBI_6715 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6715 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_6715 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_6715 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_6715 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6715 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6715 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6715 NIFSTD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/27707001 SNOMEDCT CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008525 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4019810 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4019810 VANDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/36621009 SNOMEDCT CUI
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http://purl.bioontology.org/ontology/MSHFRE/D008525 MSHFRE CUI
http://purl.bioontology.org/ontology/MESH/D008525 MESH CUI
http://purl.bioontology.org/ontology/MESH/D008525 MESH LOOM
http://purl.bioontology.org/ontology/RCD/x02Z7 RCD CUI
http://purl.bioontology.org/ontology/SNMI/C-A1221 SNMI CUI