Preferred Name |
methoxsalen |
|
Synonyms |
Xanthotoxin |
|
Definitions |
A naturally occurring substance isolated from the seeds of the plant Ammi majus with photoactivating properties. As a member of the family of compounds known as psoralens or furocoumarins, methoxsalen's exact mechanism of action is unknown; upon photoactivation, methoxsalen has been observed to bind covalently to and crosslink DNA. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C643" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C643" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039499 |
|
altLabel |
Xanthotoxin Meladinine Geroxalen Metoxaleno 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one Geralen Ammoidin 8-methoxypsoralen Uvadex Dermox Oxsoralen-Ultra Oxsoralen Mopsoralen 8-MOP Methoxypsoralen Meladinina Deltasoralen Puvasoralen Ultramop |
|
CAS Registry |
298-81-7 |
|
cui |
C1513222 C0740127 C1513218 C0722357 C0740123 C1513215 C1513217 C0025684 C0939735 C1513219 C1513221 C1513223 C1513216 |
|
Date last modified |
2006-08-29 |
|
definition |
A naturally occurring substance isolated from the seeds of the plant Ammi majus with photoactivating properties. As a member of the family of compounds known as psoralens or furocoumarins, methoxsalen's exact mechanism of action is unknown; upon photoactivation, methoxsalen has been observed to bind covalently to and crosslink DNA. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C643" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C643" NCI Thesaurus) |
|
Legacy PDQ ID |
2132 |
|
LT |
TRD |
|
NCI ID |
C643 |
|
notation |
CDR0000039499 |
|
NSC Code |
45923 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
methoxsalen |
|
tui |
T109 T123 T121 |