Physician Data Query

Last uploaded: April 29, 2019
Preferred Name

bleomycin

Synonyms

BLM

Definitions

A mixture of glycopeptide antineoplastic antibiotics isolated from the fungus Streptomyces verticillus. Bleomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39139&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39139&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C313" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039139

altLabel

BLM

Blenoxane

BLEO

bleomycin sulfate

CAS Registry

11056-06-7

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000041983

http://purl.bioontology.org/ontology/PDQ/CDR0000040417

http://purl.bioontology.org/ontology/PDQ/CDR0000039773

http://purl.bioontology.org/ontology/PDQ/CDR0000039700

http://purl.bioontology.org/ontology/PDQ/CDR0000039113

http://purl.bioontology.org/ontology/PDQ/CDR0000039370

http://purl.bioontology.org/ontology/PDQ/CDR0000041583

http://purl.bioontology.org/ontology/PDQ/CDR0000040864

http://purl.bioontology.org/ontology/PDQ/CDR0000040590

http://purl.bioontology.org/ontology/PDQ/CDR0000039686

http://purl.bioontology.org/ontology/PDQ/CDR0000039528

http://purl.bioontology.org/ontology/PDQ/CDR0000043553

http://purl.bioontology.org/ontology/PDQ/CDR0000040802

http://purl.bioontology.org/ontology/PDQ/CDR0000039562

http://purl.bioontology.org/ontology/PDQ/CDR0000043052

http://purl.bioontology.org/ontology/PDQ/CDR0000040239

http://purl.bioontology.org/ontology/PDQ/CDR0000041909

http://purl.bioontology.org/ontology/PDQ/CDR0000039322

http://purl.bioontology.org/ontology/PDQ/CDR0000040889

http://purl.bioontology.org/ontology/PDQ/CDR0000039471

http://purl.bioontology.org/ontology/PDQ/CDR0000038582

http://purl.bioontology.org/ontology/PDQ/CDR0000040867

http://purl.bioontology.org/ontology/PDQ/CDR0000042590

http://purl.bioontology.org/ontology/PDQ/CDR0000040503

http://purl.bioontology.org/ontology/PDQ/CDR0000040395

http://purl.bioontology.org/ontology/PDQ/CDR0000043106

http://purl.bioontology.org/ontology/PDQ/CDR0000039397

http://purl.bioontology.org/ontology/PDQ/CDR0000039378

http://purl.bioontology.org/ontology/PDQ/CDR0000042037

http://purl.bioontology.org/ontology/PDQ/CDR0000039098

http://purl.bioontology.org/ontology/PDQ/CDR0000039463

http://purl.bioontology.org/ontology/PDQ/CDR0000039611

http://purl.bioontology.org/ontology/PDQ/CDR0000041693

http://purl.bioontology.org/ontology/PDQ/CDR0000042930

http://purl.bioontology.org/ontology/PDQ/CDR0000041805

http://purl.bioontology.org/ontology/PDQ/CDR0000039401

http://purl.bioontology.org/ontology/PDQ/CDR0000042041

http://purl.bioontology.org/ontology/PDQ/CDR0000357354

http://purl.bioontology.org/ontology/PDQ/CDR0000040787

http://purl.bioontology.org/ontology/PDQ/CDR0000038574

http://purl.bioontology.org/ontology/PDQ/CDR0000040866

http://purl.bioontology.org/ontology/PDQ/CDR0000039520

http://purl.bioontology.org/ontology/PDQ/CDR0000042269

http://purl.bioontology.org/ontology/PDQ/CDR0000040244

http://purl.bioontology.org/ontology/PDQ/CDR0000039387

http://purl.bioontology.org/ontology/PDQ/CDR0000040401

http://purl.bioontology.org/ontology/PDQ/CDR0000039685

http://purl.bioontology.org/ontology/PDQ/CDR0000039977

http://purl.bioontology.org/ontology/PDQ/CDR0000042016

http://purl.bioontology.org/ontology/PDQ/CDR0000042946

http://purl.bioontology.org/ontology/PDQ/CDR0000039374

http://purl.bioontology.org/ontology/PDQ/CDR0000042224

http://purl.bioontology.org/ontology/PDQ/CDR0000042080

http://purl.bioontology.org/ontology/PDQ/CDR0000041508

http://purl.bioontology.org/ontology/PDQ/CDR0000039391

http://purl.bioontology.org/ontology/PDQ/CDR0000042661

http://purl.bioontology.org/ontology/PDQ/CDR0000039381

http://purl.bioontology.org/ontology/PDQ/CDR0000041653

http://purl.bioontology.org/ontology/PDQ/CDR0000040453

http://purl.bioontology.org/ontology/PDQ/CDR0000038873

http://purl.bioontology.org/ontology/PDQ/CDR0000039619

http://purl.bioontology.org/ontology/PDQ/CDR0000315772

http://purl.bioontology.org/ontology/PDQ/CDR0000039399

http://purl.bioontology.org/ontology/PDQ/CDR0000040470

http://purl.bioontology.org/ontology/PDQ/CDR0000039445

http://purl.bioontology.org/ontology/PDQ/CDR0000040283

http://purl.bioontology.org/ontology/PDQ/CDR0000039364

http://purl.bioontology.org/ontology/PDQ/CDR0000039406

http://purl.bioontology.org/ontology/PDQ/CDR0000039377

http://purl.bioontology.org/ontology/PDQ/CDR0000042161

http://purl.bioontology.org/ontology/PDQ/CDR0000041317

http://purl.bioontology.org/ontology/PDQ/CDR0000039613

http://purl.bioontology.org/ontology/PDQ/CDR0000042461

http://purl.bioontology.org/ontology/PDQ/CDR0000041423

http://purl.bioontology.org/ontology/PDQ/CDR0000041062

http://purl.bioontology.org/ontology/PDQ/CDR0000040334

http://purl.bioontology.org/ontology/PDQ/CDR0000042940

http://purl.bioontology.org/ontology/PDQ/CDR0000042268

http://purl.bioontology.org/ontology/PDQ/CDR0000039702

http://purl.bioontology.org/ontology/PDQ/CDR0000038443

http://purl.bioontology.org/ontology/PDQ/CDR0000041421

http://purl.bioontology.org/ontology/PDQ/CDR0000043259

http://purl.bioontology.org/ontology/PDQ/CDR0000040803

http://purl.bioontology.org/ontology/PDQ/CDR0000040154

http://purl.bioontology.org/ontology/PDQ/CDR0000040922

http://purl.bioontology.org/ontology/PDQ/CDR0000042055

http://purl.bioontology.org/ontology/PDQ/CDR0000043683

http://purl.bioontology.org/ontology/PDQ/CDR0000039465

http://purl.bioontology.org/ontology/PDQ/CDR0000039682

http://purl.bioontology.org/ontology/PDQ/CDR0000041288

http://purl.bioontology.org/ontology/PDQ/CDR0000039311

http://purl.bioontology.org/ontology/PDQ/CDR0000041692

http://purl.bioontology.org/ontology/PDQ/CDR0000040895

http://purl.bioontology.org/ontology/PDQ/CDR0000039701

http://purl.bioontology.org/ontology/PDQ/CDR0000040865

http://purl.bioontology.org/ontology/PDQ/CDR0000041650

http://purl.bioontology.org/ontology/PDQ/CDR0000039359

http://purl.bioontology.org/ontology/PDQ/CDR0000039618

http://purl.bioontology.org/ontology/PDQ/CDR0000040082

http://purl.bioontology.org/ontology/PDQ/CDR0000041369

http://purl.bioontology.org/ontology/PDQ/CDR0000039372

http://purl.bioontology.org/ontology/PDQ/CDR0000039349

http://purl.bioontology.org/ontology/PDQ/CDR0000361549

http://purl.bioontology.org/ontology/PDQ/CDR0000039385

http://purl.bioontology.org/ontology/PDQ/CDR0000040398

http://purl.bioontology.org/ontology/PDQ/CDR0000039612

http://purl.bioontology.org/ontology/PDQ/CDR0000042511

http://purl.bioontology.org/ontology/PDQ/CDR0000041422

http://purl.bioontology.org/ontology/PDQ/CDR0000038461

http://purl.bioontology.org/ontology/PDQ/CDR0000040868

http://purl.bioontology.org/ontology/PDQ/CDR0000040936

http://purl.bioontology.org/ontology/PDQ/CDR0000040074

http://purl.bioontology.org/ontology/PDQ/CDR0000043418

http://purl.bioontology.org/ontology/PDQ/CDR0000039368

http://purl.bioontology.org/ontology/PDQ/CDR0000422413

http://purl.bioontology.org/ontology/PDQ/CDR0000315771

http://purl.bioontology.org/ontology/PDQ/CDR0000037980

http://purl.bioontology.org/ontology/PDQ/CDR0000042931

http://purl.bioontology.org/ontology/PDQ/CDR0000042685

http://purl.bioontology.org/ontology/PDQ/CDR0000039355

cui

C0701921

C0005739

C0005740

Date last modified

2006-07-27

definition

A mixture of glycopeptide antineoplastic antibiotics isolated from the fungus Streptomyces verticillus. Bleomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39139&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39139&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C313" NCI Thesaurus)

IND Code

6649

Legacy PDQ ID

176

NCI ID

C313

notation

CDR0000039139

NSC Code

125066

ORIG STY

Drug/agent

prefLabel

bleomycin

tui

T116

T195

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