loading...| Preferred Name |
bupropion hydrochloride |
|
| Synonyms |
Forfivo XL (+-)-1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride BW 323U66 Zyban Wellbutrin Amfebutamone |
|
| Definitions |
The hydrochloride salt of an aminoketone antidepressant. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine. Buproprion also weakly inhibits the neuronal re-uptake of dopamine. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1317" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1317" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000038567 |
|
| altLabel |
Forfivo XL (+-)-1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride BW 323U66 Zyban Wellbutrin Amfebutamone |
|
| CAS Registry |
31677-93-7 |
|
| Component of | ||
| cui |
C0751626 C1524101 C0085208 C0700563 C0085934 C3272321 |
|
| Date last modified |
2017-10-11 |
|
| definition |
The hydrochloride salt of an aminoketone antidepressant. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine. Buproprion also weakly inhibits the neuronal re-uptake of dopamine. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1317" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1317" NCI Thesaurus) |
|
| Legacy PDQ ID |
11198 |
|
| LT |
TRD |
|
| NCI ID |
C1317 |
|
| notation |
CDR0000038567 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
bupropion hydrochloride |
|
| tui |
T109 T121 |