loading...| Preferred Name |
orphenadrine citrate |
|
| Synonyms |
Norflex |
|
| Definitions |
The citrate salt form of orphenadrine with a muscle relaxant property. Although the mechanism of action has not been fully elucidated, orphenadrine citrate appears to block cholinergic receptors, thereby interfering with the transmission of nerve impulses from the spinal cord to the muscles. It does not produce myoneural block, nor does it affect crossed extensor reflexes. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47641" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47641" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000787125 |
|
| altLabel |
Norflex |
|
| CAS Registry |
4682-36-4 |
|
| cui |
C0029310 C0877881 |
|
| DATE FIRST PUBLISHED |
2017-02-23 |
|
| Date last modified |
2017-02-23 |
|
| definition |
The citrate salt form of orphenadrine with a muscle relaxant property. Although the mechanism of action has not been fully elucidated, orphenadrine citrate appears to block cholinergic receptors, thereby interfering with the transmission of nerve impulses from the spinal cord to the muscles. It does not produce myoneural block, nor does it affect crossed extensor reflexes. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47641" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47641" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C47641 |
|
| notation |
CDR0000787125 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
orphenadrine citrate |
|
| tui |
T109 T121 |