loading...| Preferred Name |
oxybutynin chloride |
|
| Synonyms |
4-(diethylamino)-2-butynyl ()-,alpha-phenylcyclohexaneglycolate hydrochloride |
|
| Definitions |
The chloride salt form of oxybutynin, a tertiary amine and anticholinergic agent with antispasmodic activity. Oxybutynin chloride exerts its antimuscarinic effect on bladder smooth muscle by blocking muscarinic receptors in smooth muscle, thereby inhibiting acetylcholine binding. This results in a relaxation of bladder smooth muscle, a reduction of involuntary muscle contractions and delays the initial desire to void. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C73597" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C73597" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000785751 |
|
| altLabel |
4-(diethylamino)-2-butynyl ()-,alpha-phenylcyclohexaneglycolate hydrochloride Gelnique MJ-4309-1 oxybutynin hydrochloride Ditropan |
|
| CAS Registry |
1508-65-2 |
|
| cui |
C3282889 C0591395 C0134394 C2609648 |
|
| DATE FIRST PUBLISHED |
2016-12-14 |
|
| Date last modified |
2016-12-14 |
|
| definition |
The chloride salt form of oxybutynin, a tertiary amine and anticholinergic agent with antispasmodic activity. Oxybutynin chloride exerts its antimuscarinic effect on bladder smooth muscle by blocking muscarinic receptors in smooth muscle, thereby inhibiting acetylcholine binding. This results in a relaxation of bladder smooth muscle, a reduction of involuntary muscle contractions and delays the initial desire to void. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C73597" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C73597" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C73597 |
|
| notation |
CDR0000785751 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
oxybutynin chloride |
|
| tui |
T109 T121 |