Preferred Name |
ropinirole hydrochloride |
|
Synonyms |
SK&F 101468-A |
|
Definitions |
The hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparkinsonian property. Acting as a substitute for dopamine, ropinirole hydrochloride binds to and activates dopamine D2 and D3 receptors within the caudate putamen in the brain, thereby improving motor function. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47710" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47710" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000779013 |
|
altLabel |
SK&F 101468-A Requip 4-(2-(dipropylamino)ethyl)-2-indolinone monohydrochloride 2(H)-indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-, monohydrochloride |
|
CAS Registry |
91374-20-8 |
|
cui |
C0771840 C0593342 C2949746 |
|
DATE FIRST PUBLISHED |
2016-02-24 |
|
Date last modified |
2016-02-24 |
|
definition |
The hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparkinsonian property. Acting as a substitute for dopamine, ropinirole hydrochloride binds to and activates dopamine D2 and D3 receptors within the caudate putamen in the brain, thereby improving motor function. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47710" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47710" NCI Thesaurus) |
|
LT |
TRD |
|
NCI ID |
C47710 |
|
notation |
CDR0000779013 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
ropinirole hydrochloride |
|
tui |
T109 T121 |