loading...| Preferred Name |
repaglinide |
|
| Synonyms |
AG-EE 623 ZW |
|
| Definitions |
A nonsulfonylurea insulin secretagogue belonging to the melgitinide class with hypoglycemic activity. Repaglinide is rapidly absorbed and has a rapid onset and short duration of action. This agent is metabolized in the liver by CYP2C8 and CYP3A4 and its metabolites are excreted in the bile. Repaglinide has a half-life of one hour. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47703" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47703" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000775334 |
|
| altLabel |
AG-EE 623 ZW benzoic acid, 2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)-,(S)- Prandin (+)-2-ethoxy-alpha-(((S)-alpha-isobutyl-o-piperidinobenzyl)carbamoyl)-p-toluic acid |
|
| CAS Registry |
135062-02-1 |
|
| cui |
C0246689 C0722725 C0287495 |
|
| DATE FIRST PUBLISHED |
2015-09-03 |
|
| Date last modified |
2015-09-03 |
|
| definition |
A nonsulfonylurea insulin secretagogue belonging to the melgitinide class with hypoglycemic activity. Repaglinide is rapidly absorbed and has a rapid onset and short duration of action. This agent is metabolized in the liver by CYP2C8 and CYP3A4 and its metabolites are excreted in the bile. Repaglinide has a half-life of one hour. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47703" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47703" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C47703 |
|
| notation |
CDR0000775334 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
repaglinide |
|
| tui |
T109 T121 |