loading...| Preferred Name |
lidocaine patch 5% |
|
| Synonyms |
Lidoderm |
|
| Definitions |
A transdermal patch containing a 5 percent aqueous base solution of the synthetic amide-type anesthetic lidocaine with analgesic activity. Upon topical application and transdermal delivery, the active ingredient lidocaine binds to and blocks voltage-gated sodium channels in the neuronal cell membrane; lidocaine-mediated stabilization of neuronal membranes inhibits the initiation and conduction of nerve impulses and produces a reversible local anesthesia. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29988" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29988" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000598079 |
|
| altLabel |
Lidoderm |
|
| cui |
C0794811 C0876068 |
|
| DATE FIRST PUBLISHED |
2008-06-10 |
|
| Date last modified |
2009-01-29 |
|
| definition |
A transdermal patch containing a 5 percent aqueous base solution of the synthetic amide-type anesthetic lidocaine with analgesic activity. Upon topical application and transdermal delivery, the active ingredient lidocaine binds to and blocks voltage-gated sodium channels in the neuronal cell membrane; lidocaine-mediated stabilization of neuronal membranes inhibits the initiation and conduction of nerve impulses and produces a reversible local anesthesia. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29988" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29988" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C29988 |
|
| notation |
CDR0000598079 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
lidocaine patch 5% |
|
| tui |
T109 T200 T121 |