loading...| Preferred Name |
escitalopram oxalate |
|
| Synonyms |
5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-,(1S)-, ethanedioate(1:1) |
|
| Definitions |
The oxalate salt of escitalopram, a pure S-enantiomer of the racemic bicyclic phthalane derivative citalopram, with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), escitalopram blocks the reuptake of serotonin by neurons in the central nervous system (CNS), thereby potentiating CNS serotonergic activity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47518" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47518" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000497135 |
|
| altLabel |
5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-,(1S)-, ethanedioate(1:1) Lexapro Lu 26-054-0 |
|
| CAS Registry |
219861-08-2 |
|
| cui |
C1765323 C1170746 C1170371 |
|
| DATE FIRST PUBLISHED |
2006-07-25 |
|
| definition |
The oxalate salt of escitalopram, a pure S-enantiomer of the racemic bicyclic phthalane derivative citalopram, with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), escitalopram blocks the reuptake of serotonin by neurons in the central nervous system (CNS), thereby potentiating CNS serotonergic activity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47518" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47518" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C47518 |
|
| notation |
CDR0000497135 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
escitalopram oxalate |
|
| tui |
T109 T121 |