loading...| Preferred Name |
apixaban |
|
| Synonyms |
BMS-562247 |
|
| Definitions |
An orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing formation of cross-linked fibrin clots. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C61308" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61308" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000484444 |
|
| altLabel |
BMS-562247 1H-Pyrazolo(3,4-c)pyridine-3-carboxamide, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)- BMS-562247-01 aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19.alpha.)-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) Eliquis |
|
| CAS Registry |
503612-47-3 |
|
| cui |
C1831809 C3530466 C1831808 |
|
| DATE FIRST PUBLISHED |
2006-05-05 |
|
| Date last modified |
2015-11-05 |
|
| definition |
An orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing formation of cross-linked fibrin clots. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C61308" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61308" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C61308 |
|
| notation |
CDR0000484444 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
apixaban |
|
| tui |
T109 T121 |