loading...| Preferred Name |
tamsulosin hydrochloride |
|
| Synonyms |
Flomax |
|
| Definitions |
The hydrochloride salt of tamsulosin, a sulfonamide derivative with adrenergic antagonist activity. Tamsulosin selectivity binds to and blocks the activity of alpha1 adrenoreceptors in the human prostate and bladder neck; blockade of these adrenoceptors can cause smooth muscle in the prostate and bladder neck to relax, resulting in an improvement in urinary flow rate. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29486" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29486" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000479148 |
|
| altLabel |
Flomax |
|
| cui |
C0662903 C0771774 |
|
| DATE FIRST PUBLISHED |
2006-04-07 |
|
| Date last modified |
2008-03-05 |
|
| definition |
The hydrochloride salt of tamsulosin, a sulfonamide derivative with adrenergic antagonist activity. Tamsulosin selectivity binds to and blocks the activity of alpha1 adrenoreceptors in the human prostate and bladder neck; blockade of these adrenoceptors can cause smooth muscle in the prostate and bladder neck to relax, resulting in an improvement in urinary flow rate. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29486" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29486" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C29486 |
|
| notation |
CDR0000479148 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
tamsulosin hydrochloride |
|
| tui |
T109 T121 |