Preferred Name |
recombinant interferon alpha-2a |
|
Synonyms |
Roceron-A |
|
Definitions |
A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1952" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1952" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000467189 |
|
altLabel |
Roceron-A alpha 2 interferon Roferon-A Laroferon interferon alfa 2a IFN alpha-2A interferon alfa-2a rHuIFN-a 2a recombinant interferon alfa-2a IFN-alpha 2 |
|
CAS Registry |
76543-88-9 |
|
cui |
C0699179 C0021734 C1512831 C1512832 |
|
DATE FIRST PUBLISHED |
2006-02-21 |
|
Date last modified |
2017-12-14 |
|
definition |
A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1952" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1952" NCI Thesaurus) |
|
LT |
TRD |
|
NCI ID |
C1952 |
|
notation |
CDR0000467189 |
|
NSC Code |
367982 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
recombinant interferon alpha-2a |
|
tui |
T116 T129 T121 |