loading...| Preferred Name |
triptorelin |
|
| Synonyms |
TRIP |
|
| Definitions |
A synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1267" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1267" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042944 |
|
| altLabel |
TRIP Decapeptyl CL-118,532 6-D-Tryptophan-LH-RH 6-D-Tryptophanluteinizing Hormone-releasing Factor Detryptoreline AY-25650 D-TRP-6-LHRH |
|
| CAS Registry |
57773-63-4 |
|
| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000285615 http://purl.bioontology.org/ontology/PDQ/CDR0000322248 http://purl.bioontology.org/ontology/PDQ/CDR0000285616 http://purl.bioontology.org/ontology/PDQ/CDR0000043340 |
|
| cui |
C0701190 C0077275 C0701191 C2745954 |
|
| Date last modified |
2006-09-28 |
|
| definition |
A synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1267" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1267" NCI Thesaurus) |
|
| Legacy PDQ ID |
699 |
|
| LT |
TRD |
|
| NCI ID |
C1267 |
|
| notation |
CDR0000042944 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
triptorelin |
|
| tui |
T125 T116 T121 |