loading...| Preferred Name |
hereditary retinoblastoma |
|
| Synonyms |
Familial Retinoblastoma |
|
| Definitions |
An inherited malignant tumor that originates in the nuclear layer of the retina. A predisposition to retinoblastoma has been associated with 13q14 cytogenetic abnormalities. Patients with the inherited form appear to be at increased risk for secondary nonocular malignancies such as osteosarcoma, malignant fibrous histiocytoma, and fibrosarcoma. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C8495" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C8495" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042842 |
|
| altLabel |
Familial Retinoblastoma retinoblastoma, hereditary |
|
| Associated disease |
http://purl.bioontology.org/ontology/PDQ/CDR0000636561 http://purl.bioontology.org/ontology/PDQ/CDR0000039836 http://purl.bioontology.org/ontology/PDQ/CDR0000038825 http://purl.bioontology.org/ontology/PDQ/CDR0000043733 http://purl.bioontology.org/ontology/PDQ/CDR0000040252 http://purl.bioontology.org/ontology/PDQ/CDR0000041729 http://purl.bioontology.org/ontology/PDQ/CDR0000040209 http://purl.bioontology.org/ontology/PDQ/CDR0000043673 http://purl.bioontology.org/ontology/PDQ/CDR0000041746 |
|
| cui |
C0751483 |
|
| Date last modified |
2012-02-13 |
|
| definition |
An inherited malignant tumor that originates in the nuclear layer of the retina. A predisposition to retinoblastoma has been associated with 13q14 cytogenetic abnormalities. Patients with the inherited form appear to be at increased risk for secondary nonocular malignancies such as osteosarcoma, malignant fibrous histiocytoma, and fibrosarcoma. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C8495" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C8495" NCI Thesaurus) |
|
| Legacy PDQ ID |
6647 |
|
| NCI ID |
C8495 |
|
| notation |
CDR0000042842 |
|
| ORIG STY |
Genetic condition |
|
| prefLabel |
hereditary retinoblastoma |
|
| tui |
T191 |
|
| subClassOf |