loading...| Preferred Name |
goserelin acetate |
|
| Synonyms |
Zoladex |
|
| Definitions |
The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04) Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1417" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1417" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000040224 |
|
| altLabel |
Zoladex ZDX D-Ser(bu(t))(6)azgly(10)-LHRH acetate |
|
| CAS Registry |
65807-02-5 |
|
| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000038565 http://purl.bioontology.org/ontology/PDQ/CDR0000362077 http://purl.bioontology.org/ontology/PDQ/CDR0000042091 http://purl.bioontology.org/ontology/PDQ/CDR0000357941 http://purl.bioontology.org/ontology/PDQ/CDR0000038197 http://purl.bioontology.org/ontology/PDQ/CDR0000038769 http://purl.bioontology.org/ontology/PDQ/CDR0000038845 http://purl.bioontology.org/ontology/PDQ/CDR0000041316 http://purl.bioontology.org/ontology/PDQ/CDR0000428223 http://purl.bioontology.org/ontology/PDQ/CDR0000041770 http://purl.bioontology.org/ontology/PDQ/CDR0000042084 http://purl.bioontology.org/ontology/PDQ/CDR0000420970 http://purl.bioontology.org/ontology/PDQ/CDR0000358199 http://purl.bioontology.org/ontology/PDQ/CDR0000410697 http://purl.bioontology.org/ontology/PDQ/CDR0000043652 http://purl.bioontology.org/ontology/PDQ/CDR0000362079 http://purl.bioontology.org/ontology/PDQ/CDR0000041106 http://purl.bioontology.org/ontology/PDQ/CDR0000038844 http://purl.bioontology.org/ontology/PDQ/CDR0000358333 http://purl.bioontology.org/ontology/PDQ/CDR0000042088 http://purl.bioontology.org/ontology/PDQ/CDR0000041107 |
|
| cui |
C0149473 C0700476 |
|
| Date last modified |
2017-11-06 |
|
| definition |
The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04) Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1417" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1417" NCI Thesaurus) |
|
| Legacy PDQ ID |
3035 |
|
| LT |
TRD |
|
| NCI ID |
C1417 |
|
| notation |
CDR0000040224 |
|
| NSC Code |
606864 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
goserelin acetate |
|
| tui |
T125 T116 T121 |