loading...| Preferred Name |
myelodysplastic syndromes |
|
| Synonyms |
dysmyelopoiesis Smoldering Leukemia |
|
| Definitions |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C3247" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C3247" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039817 |
|
| altLabel |
dysmyelopoiesis MDS myelodysplasia Oligoblastic Leukemia Myelodysplastic Syndrome Dysmyelopoietic Syndrome Myelodysplastic syndromes preleukemia Smoldering Leukemia |
|
| cui |
C3463824 |
|
| definition |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C3247" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C3247" NCI Thesaurus) |
|
| Legacy PDQ ID |
2495 |
|
| MENU PARENT |
Disease/diagnosis |
|
| MENU TYPE |
Clinical Trials--CancerType |
|
| NCI ID |
C3247 |
|
| notation |
CDR0000039817 |
|
| ORIG STY |
Neoplasm diagnosis |
|
| prefLabel |
myelodysplastic syndromes |
|
| tui |
T191 |
|
| subClassOf |