Preferred Name |
phosphorus P32 |
|
Synonyms |
P32 |
|
Definitions |
A radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular biological macromolecules, resulting in tumor cell death. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1698" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1698" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039554 |
|
altLabel |
P32 32-P |
|
cui |
C0851287 |
|
Date last modified |
2010-06-07 |
|
definition |
A radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular biological macromolecules, resulting in tumor cell death. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1698" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1698" NCI Thesaurus) |
|
Legacy PDQ ID |
2203 |
|
NCI ID |
C1698 |
|
notation |
CDR0000039554 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
phosphorus P32 |
|
tui |
T130 T196 T121 |