Preferred Name |
betamethasone |
|
Synonyms |
Celestone |
|
Definitions |
A synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C303" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C303" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039273 |
|
altLabel |
Celestone |
|
CAS Registry |
378-44-9 |
|
cui |
C0701247 C0005308 |
|
definition |
A synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C303" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C303" NCI Thesaurus) |
|
Legacy PDQ ID |
1903 |
|
LT |
TRD |
|
NCI ID |
C303 |
|
notation |
CDR0000039273 |
|
NSC Code |
39470 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
betamethasone |
|
tui |
T125 T109 T121 |