Prostate Cancer Ontology

Last uploaded: June 6, 2023
Preferred Name

Goserelin

Synonyms
Definitions

A synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity. Goserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of goserelin inhibits the secretion of pituitary gonadotropin, thereby decreasing levels of testosterone (in males) and estradiol (in females). Administration of this agent in a depot formulation may result in the regression of sex hormone-sensitive tumors and a reduction in sex organ size and function. (NCI04)/NCI-GLOSS Definition: A drug that belongs to the family of drugs called gonadotropin-releasing hormone analogues. Goserelin is used to block hormone production in the ovaries or testicles.

ID

http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Goserelin

ChineseLabel

戈舍瑞林

definition

A synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity. Goserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of goserelin inhibits the secretion of pituitary gonadotropin, thereby decreasing levels of testosterone (in males) and estradiol (in females). Administration of this agent in a depot formulation may result in the regression of sex hormone-sensitive tumors and a reduction in sex organ size and function. (NCI04)/NCI-GLOSS Definition: A drug that belongs to the family of drugs called gonadotropin-releasing hormone analogues. Goserelin is used to block hormone production in the ovaries or testicles.

label

Goserelin

prefixIRI

ProstateCancer:Goserelin

prefLabel

Goserelin

reference

NCI Thesaurus Code:C1374

synonyms

6-[O-(1,1-Dimethylethyl)-D-serine]-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) 2-(aminocarbonyl)hydrazide

GOSERELIN

Goserelin

ICI-118630

goserelin

URL

https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C1374

subClassOf

http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Medical_castration

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http://purl.obolibrary.org/obo/CHEBI_5523 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_5523 CHEBI LOOM
http://purl.bioontology.org/ontology/MESH/D017273 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D017273 RH-MESH LOOM
http://purl.obolibrary.org/obo/dinto_DB00014 DINTO LOOM
http://purl.obolibrary.org/obo/MESH_D017273 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.548.365.740.320.340 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D06.472.699.327.740.320.340 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00019104 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/OMIT_0017655 OMIT LOOM
http://purl.obolibrary.org/obo/CHEBI_5523 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_5523 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_5523 GSSO LOOM
http://purl.obolibrary.org/obo/CHEBI_5523 DRON LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1374 NCIT LOOM
http://purl.bioontology.org/ontology/NDDF/006407 NDDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0120107 OCHV LOOM
http://stirdf.jst.go.jp/id/200907006081066831 IOBC LOOM
http://www.co-ode.org/ontologies/galen#Goserelin GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.456.460.315 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C1374 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.400.400.740.320.340 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/108771008 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#16293 OCHV LOOM
https://go.drugbank.com/drugs/DB00014 MDM LOOM
http://www.drugbank.ca/drugs/DB00014 FTC LOOM
http://purl.bioontology.org/ontology/ATC/L02AE03 ATC LOOM
http://purl.jp/bio/4/id/200906013825404130 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.641.650.405.740.320.340 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/50610 RXNORM LOOM