Orphanet Rare Disease Ontology

Last uploaded: December 13, 2023
Preferred Name

Acute myeloid leukemia with minimal differentiation

Synonyms

AML M0

Minimally differentiated acute myeloblastic leukemia

Definitions

A rare subtype of acute myeloid leukemia characterized by clonal proliferation of poorly differentiated myeloid blasts in the bone marrow, blood or other tissues. It usually presents with anemia, thrombocytopenia and other nonspecific symptoms related to ineffective hematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement (gingivitis, splenomegaly). Low remission rates are reported.

ID

http://www.orpha.net/ORDO/Orphanet_98832

alternative_term

AML M0

Minimally differentiated acute myeloblastic leukemia

definition

A rare subtype of acute myeloid leukemia characterized by clonal proliferation of poorly differentiated myeloid blasts in the bone marrow, blood or other tissues. It usually presents with anemia, thrombocytopenia and other nonspecific symptoms related to ineffective hematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement (gingivitis, splenomegaly). Low remission rates are reported.

definition_citation

Orphanet

expertlink

https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=98832

has_age_of_onset

Adult

has_inheritance

Not applicable

hasDbXref

ICD-11:2A60.30

ICD-10:C92.0

ICD-11:XH90G0

UMLS:C0522631

label

Acute myeloid leukemia with minimal differentiation

notation

ORPHA:98832

part_of

http://www.orpha.net/ORDO/Orphanet_167714

prefixIRI

ORDO:Orphanet_98832

prefLabel

Acute myeloid leukemia with minimal differentiation

present_in

Europe AND has_annual_incidence_average_value : 0.01 AND has_annual_incidence_range : <1 / 1 000 000

treeView

http://www.orpha.net/ORDO/Orphanet_167714

subClassOf

http://www.orpha.net/ORDO/Orphanet_377788

http://www.orpha.net/ORDO/Orphanet_557493

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