Orphanet Rare Disease Ontology

Last uploaded: December 13, 2023
Preferred Name

Manganese poisoning

Synonyms

Manganese intoxication

Manganism

Definitions

A rare disorder due to toxic effects characterized by a progressive, permanent affliction of the extrapyramidal system with the globus pallidus and striatum as primary targets of neurotoxic effects. Symptoms include headache, insomnia, memory loss, emotional instability, hyperreflexia, dystonia, tremor, speech disturbances, and gait abnormalities. Individual factors like age, gender, genetics, and pre-existing medical conditions appear to have a profound impact on manganese toxicity.

ID

http://www.orpha.net/ORDO/Orphanet_306682

alternative_term

Manganese intoxication

Manganism

definition

A rare disorder due to toxic effects characterized by a progressive, permanent affliction of the extrapyramidal system with the globus pallidus and striatum as primary targets of neurotoxic effects. Symptoms include headache, insomnia, memory loss, emotional instability, hyperreflexia, dystonia, tremor, speech disturbances, and gait abnormalities. Individual factors like age, gender, genetics, and pre-existing medical conditions appear to have a profound impact on manganese toxicity.

definition_citation

Orphanet

expertlink

https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=306682

hasDbXref

MedDRA:10058951

UMLS:C0677050

MeSH:D020149

ICD-10:T57.2

ICD-11:NE61

label

Manganese poisoning

notation

ORPHA:306682

part_of

http://www.orpha.net/ORDO/Orphanet_556508

http://www.orpha.net/ORDO/Orphanet_306679

prefixIRI

ORDO:Orphanet_306682

prefLabel

Manganese poisoning

treeView

http://www.orpha.net/ORDO/Orphanet_556508

http://www.orpha.net/ORDO/Orphanet_306679

subClassOf

http://www.orpha.net/ORDO/Orphanet_377788

http://www.orpha.net/ORDO/Orphanet_557493

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