loading...| Preferred Name |
Recombinant Platelet-Derived Growth Factor |
|
| Synonyms |
Platlet-Derived Growth Factor rPDGF |
|
| Definitions |
Expressed in platelets, human Platelet-Derived Growth Factor (PDGF/VEGF Family) is a mitogenic factor for mesenchymal cells characterized by a motif of eight cysteines and released upon wounding to stimulate adjacent cell growth. PDGF can exist as antiparallel disulfide-linked homodimers (PDGFA, PDGFB) or heterodimers (PDGFA/PDGFB) that could bind to PDGF receptor and may elicit a variety of cellular responses. A and B homodimers are implicated in transformation processes. (NCI) (source : NCI) |
|
| ID |
http://doe-generated-ontology.com/OntoAD#C1515387 |
|
| altLabel |
Platlet-Derived Growth Factor rPDGF |
|
| definition |
Expressed in platelets, human Platelet-Derived Growth Factor (PDGF/VEGF Family) is a mitogenic factor for mesenchymal cells characterized by a motif of eight cysteines and released upon wounding to stimulate adjacent cell growth. PDGF can exist as antiparallel disulfide-linked homodimers (PDGFA, PDGFB) or heterodimers (PDGFA/PDGFB) that could bind to PDGF receptor and may elicit a variety of cellular responses. A and B homodimers are implicated in transformation processes. (NCI) (source : NCI) |
|
| hiddenLabel |
RecombinantPlatelet-DerivedGrowthFactor |
|
| prefixIRI |
OntoAD:C1515387 |
|
| prefLabel |
Recombinant Platelet-Derived Growth Factor |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C755 | NCIT | LOOM | |
| http://purl.obolibrary.org/obo/NCIT_C755 | BERO | LOOM |