loading...| Preferred Name |
Memantine hydrochloride |
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| Synonyms |
memantine HCl |
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| Definitions |
The hydrochloride salt of memantine, a low-affinity, voltage-dependent, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine binds to and inhibits cation channels of glutamanergic NMDA receptors located in the central nervous system (CNS), preventing the prolonged influx of calcium ions and the associated neuronal excitotoxicity, and thereby potentially enhancing cognitive function. Memantine is also a 5-hydroxytryptamine type 3 (5HT3) receptor and nicotinic receptor antagon (source : ) |
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| ID |
http://doe-generated-ontology.com/OntoAD#C0771988 |
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| altLabel |
memantine HCl Ebixia antiparkinsonism drugs memantine hydrochloride |
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| definition |
The hydrochloride salt of memantine, a low-affinity, voltage-dependent, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine binds to and inhibits cation channels of glutamanergic NMDA receptors located in the central nervous system (CNS), preventing the prolonged influx of calcium ions and the associated neuronal excitotoxicity, and thereby potentially enhancing cognitive function. Memantine is also a 5-hydroxytryptamine type 3 (5HT3) receptor and nicotinic receptor antagon (source : ) |
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| hiddenLabel |
ChlorhydrateDeMémantine MemantineHydrochloride |
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| prefixIRI |
OntoAD:C0771988 |
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| prefLabel |
Memantine hydrochloride Chlorhydrate de mémantine |
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| subClassOf |